Fred Madison has killed his wife Renee, but why does he not remember doing it?
Why is Fred opposed to video cameras and what does this have to do with Pete Dayton and his friend, the powerful gangster, Mr. Eddy?
What is the meaning of the strange video tapes Fred and Renee receive every morning?
The answers to these questions may be discovered at the end of the Lost Highway...but is there an end?
Actors: Bill Pullman, Patricia Arquette, Balthazar Getty
Director: David Lynch